出版刊物

PUBLICATIONS

Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway
Chen YA, Shen YL, Hsia HY, Tiang YP, Sung TL, Chen LY Nat. Struct. Mol. Biol. 2017
中研院2017年重要研究成果，由中研院招開記者會，獲得包含聯合報，自由時報在內的10多家國內平面及電子媒體報導，此文亦獲F1000Prime推薦為細胞生物學與發育生物學領域重要發現...
Molecular basis of telomere syndrome caused by CTC1 mutations
Chen LY , Majerská J, Lingner J. Genes Dev. 2013
The human CST complex is a terminator of telomerase activity
Chen LY, Redon S, and Lingner J. Nature 2012
台灣端粒臨床研究齊步走！
陳律佑
和信醫院與中研院聯手開創端粒個人化精準醫療透過基礎研究與臨床醫學緊密的合作，在未來，我們可以為端粒疾病的治療帶來一片光明……

Ends end it via mitochondria: A telomere-dependent tumor suppressive mechanism acts during replicative crisis

Gaela VM and Chen LY Mol Cell. 2023
Evolution of Graves’ Disease during Immune Reconstitution following Nonmyeloablative Haploidentical Peripheral Blood Stem Cell Transplantation in a Boy Carrying Germline SAMD9L and FLT3 Variants

Ip PP, Fang LH, Shen YL, Tung KC, Lai MT, Juan LY, Chen LY and Chen RL Int J Mol Sci. 2022
XPF activates break-induced telomere synthesis

Guh CY, Shen HJ, Chen LW, Chiu PC, Liao IH, Lo CC, Chen Y, Hsieh YH, Chang TC, Yen CP, Chen YY, Chen TWW, Chen LW, Wu CS, Egly JM and Chu HPC Nat Commun. 2022
A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres

Mentegari E, Bertoletti F, Kissova M, Zucca E, Galli S, Tagliavini G, Garbelli A, Maffia A, Bione S, Ferrari E, d'Adda di Fagagna F, Francia S, Sabbioneda S, Chen LY, Lingner J, Bergoglio V, Hoffmann JS, HübschMaga U, Crespan E and Maga G International Journal of Molecular Sciences 2021
Peri-treatment adverse events of primary mediastinal non-seminomatous germ cell tumors

Chen RL, Liu CC, Ip PP, Fang LH, Shih LS and Chen LY Pediatr Blood Cancer. 2022
Monitoring telomere maintenance during regeneration of Annelids

Joseph NA, Chen CF, Chen JH and Chen LY Methods Mol Biol. 2022
Individualized Dosage Optimization for Myeloablative Conditioning before Unrelated Cord Blood Transplantation in a Diamond–Blackfan Anemia Patient with Germline RPL11 Mutation: A Case Study

Chen RL, Fang LH and Chen LY Processes 2022
Complications for a Hoyeraal–Hreidarsson Syndrome Patient with a Germline DKC1 A353V Variant Undergoing Unrelated Peripheral Blood Stem Cell Transplantation

Chen RL, Lin KK and Chen LY Int J Mol Sci. 2019
Telomere maintenance during anterior regeneration and aging in the freshwater annelid Aeolosoma viride

Chen CF, Sung TL, Chen LY and Chen JH Scientific Reports 2018
Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches

Khoo LT and Chen LY EMBO reports 2018
Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway

Chen YA, Shen YL, Hsia HY, Tiang YP, Sung TL, Chen LY Nat. Struct. Mol. Biol. 2017
中研院2017年重要研究成果，由中研院招開記者會，獲得包含聯合報，自由時報在內的10多家國內平面及電子媒體報導，此文亦獲F1000Prime推薦為細胞生物學與發育生物學領域重要發現...
Tethering CST to the telomerase catalytic core-the p50 linchpin

Joseph NA and Chen LY Structure. 2022
Long-term hematopoietic transfer of the anti-cancer and lifespan-extending capabilities of a genetically engineered blood system by transplantation of bone marrow mononuclear cells

Wang JP, Hung CH, Liou YH, Liu CC, Yeh KH, Wang KY, Lai ZS, Chatterjee B, Hsu TC, Lee TL, Shyu YC, Hsiao PW, Chen LY, Chuang TJ, Yu CA, Liao NS and Shen CJ Elife. 2024
Analysis of structure-activity relationship of indol-3-yl-N-phenylcarbamic amides as potent STING inhibitors

Chang PW, Wang JY, Wang WP, Huang WC, Wu MH, Song JS, Chen LY, Tung CW, Chi YH and Ueng SH Bioorg Med Chem. 2023
Anti-Thymocyte Globulin (ATG)-Free Nonmyeloablative Haploidentical PBSCT Plus Post-Transplantation Cyclophosphamide Is a Safe and Efficient Treatment Approach for Pediatric Acquired Aplastic Anemia

Chen RL, Ip PP, Shaw JJ, Wang YH, Fan LH, Shen YL, Joseph NA, Chen TE and Chen LY Int J Mol Sci. 2022
C-Terminal Extended Domain-Independent Telomere Maintenance: Modeling the Function of TIN2 Isoforms in Mus musculus

Huang CM, Shen YL, Ho CL, Chen TE, Hsia HY, Songyang Z and Chen LY Int. J. Mol. Sci. 2025
Orphan nuclear receptors-induced ALT-associated PML bodies are targets for ALT inhibition

Gaela VM, Hsia HY, Joseph NA, Tzeng WY, Ting PC, Shen YL, Tsai CT, Boudier T and Chen LY Nucleic Acids Research. 2024
Ends end it via mitochondria: A telomere-dependent tumor suppressive mechanism acts during replicative crisis

Gaela VM and Chen LY Molecular Cell 2023
Shorter donor leukocyte telomere length is associated with poor peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor

Yang SH, Liu HT, Wang TF, Liou YS, Sun DS, Wang JH and Chen LY J Formos Med Assoc. 2024
Incorporating innovative B-cell targeting therapeutics into a combined-modality bridging approach followed by timely consolidative haploidentical transplantation to salvage a pediatric patient with relapsed/refractory diffuse large B-cell lymphoma

Chao YJ, Lee PI, Yang TH, Fang LH, Tsai YC, Lee MY, Wang YH, Chen LY and Chen RL Pediatr Blood Cancer. 2024