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  1. 出版刊物

出版刊物

PUBLICATIONS
  • Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway
    Chen YA, Shen YL, Hsia HY, Tiang YP, Sung TL, Chen LY Nat. Struct. Mol. Biol. 2017
    中研院2017年重要研究成果,由中研院招開記者會,獲得包含聯合報,自由時報在內的10多家國內平面及電子媒體報導,此文亦獲F1000Prime推薦為細胞生物學與發育生物學領域重要發現...
  • Molecular basis of telomere syndrome caused by CTC1 mutations
    Chen LY , Majerská J, Lingner J. Genes Dev. 2013
  • The human CST complex is a terminator of telomerase activity
    Chen LY, Redon S, and Lingner J. Nature 2012
  • 台灣端粒臨床研究齊步走!
    陳律佑
    和信醫院與中研院聯手開創端粒個人化精準醫療 透過基礎研究與臨床醫學緊密的合作,在未來,我們可以為端粒疾病的治療帶來一片光明……
  • 期刊論文
  • 端粒小文
  • 書籍章節
  • Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway
    Chen YA, Shen YL, Hsia HY, Tiang YP, Sung TL, Chen LY Nat. Struct. Mol. Biol. 2017
    中研院2017年重要研究成果,由中研院招開記者會,獲得包含聯合報,自由時報在內的10多家國內平面及電子媒體報導,此文亦獲F1000Prime推薦為細胞生物學與發育生物學領域重要發現...
  • Chemotherapy for extracranial germ cell tumors in paediatric, adolescent, and young adult patients
    Chen RL, Lin HT, Chen LY EMJ Oncology 2017
  • No DDrama at chromosome ends: TRF2 takes centre stage
    Feuerhahn S, Chen LY, Luke B, Porro A Trends Biochem Sci. 2015
  • Molecular basis of telomere syndrome caused by CTC1 mutations
    Chen LY , Majerská J, Lingner J. Genes Dev. 2013
  • CST for the grand finale of telomere replication
    Chen LY and Lingner J Nucleus 2013
  • Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment
    Zhang Y, Chen LY, Han X, Hie W, Kim H, Yang D, Liu D, Songyang Z Proc Natl Acad Sci U S A. 2013
  • Mitochondrial Localization of telomeric protein TIN2 links telomere regulation to metabolic control.
    Chen LY, Zhang Y, Li H, Zhang Q, Fang H, Yotnda P, Kim SH, Qin L, Xu J, Tu B, Bai Y, Sonagyang Z Mol Cell 2012
  • The human CST complex is a terminator of telomerase activity
    Chen LY, Redon S, and Lingner J. Nature 2012
  • AUF1/hnRNP D RNA binding protein functions in telomere maintenance
    Chen LY and Lingner J Mol Cell 2012
  • CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling
    Zheng ZY, Cheng CM, Fu XR, Chen LY, Xu L, Terrillon S, Wong ST, Bar-Sagi D, Songyang Z, and Chang EC Oncogene 2012
  • Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells
    Lee OH, Kim H, He Q, Baek HJ, Yang D, Chen LY, Liang J, Chae HK, Safari A, Liu D, and Songyang Z Mol Cell Proteomics 2011
  • TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs
    Kim H, Lee OH, Xin H, Chen LY, Qin J, Chae HK, Lin SY, Safari A, Liu D, and Songyang Z Nat Struct Mol Biol 2009
  • Daxx contains two nuclear localization signals and interacts with importin alpha3
    Yeung PL, Chen LY, Tsai SC, Zhang A, and Chen JD J Cell Biochem 2008
  • Telomere maintenance through spatial control of telomeric proteins
    Chen LY, Liu D, and Songyang Z Mol Cell Biol 2007
  • Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT)
    Johnson DR, Li CW, Chen LY, Ghosh JC, and Chen JD 2006 Mol Pharmacol
  • Daxx silencing sensitizes cells to multiple apoptotic pathways
    Chen LY, and Chen JD Mol Cell Biol 2003
  • Mitochondrial calcium-mediated reactive oxygen species are essential for the rapid induction of the grp78 gene in 9L rat brain tumour cells
    Chang WM, Chen KD, Chen LY, Lai MT, and Lai YK Cell Signal 2003
  • Regulation of androgen receptor activity by the nuclear receptor corepressor SMRT
    Liao G, Chen LY, Zhang A, Godavarthy A, Xia F, Ghosh JC, Li H, and Chen JD J Biol Chem 2003
  • Activation of p38 mitogen-activated protein kinase and mitochondrial Ca(2+)-mediated oxidative stress are essential for the enhanced expression of grp78 induced by the protein phosphatase inhibitors okadaic acid and calyculin A
    Chen KD, Lai MT, Cho JH, Chen LY, and Lai YK J Cell Biochem 2000
  • Thapsigargin-induced grp78 expression is mediated by the increase of cytosolic free calcium in 9L rat brain tumor cells
    Chen LY, Chiang AS, Hung JJ, Hung HI, and Lai YK J Cell Biochem 2000
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ENGLISH
  • 研究實驗RESEARCH
  • 出版刊物PUBLICATIONS
    • 期刊論文
    • 端粒小文
    • 書籍章節
  • 成員介紹MEMBERS
  • 最新消息NEWS
    • 學術活動
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  • 聯絡我們CONTACT
  • 免責聲明
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