PUBLICATIONS(PAGE2LIST) - 中央研究院分子生物學研究所端粒科學研究室

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PUBLICATIONS

Complications for a Hoyeraal–Hreidarsson Syndrome Patient with a Germline DKC1 A353V Variant Undergoing Unrelated Peripheral Blood Stem Cell Transplantation
Chen RL, Lin KK and Chen LY Int J Mol Sci. 2019
Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway
Chen YA, Shen YL, Hsia HY, Tiang YP, Sung TL, Chen LY Nat. Struct. Mol. Biol. 2017
Molecular basis of telomere syndrome caused by CTC1 mutations
Chen LY , Majerská J, Lingner J Genes Dev. 2013
The human CST complex is a terminator of telomerase activity
Chen LY, Redon S, and Lingner J Nature 2012

Intermittent and Short-Term Empirical Ruxolitinib Regimen for Steroid-Refractory Flareups of Fibrodysplasia Ossificans Progressiva

Chen RL, Yang TH, Wang YH, Shaw JJ, Chen LY. Pharmacol Res Perspect. 2025
Leukocyte telomere length and chronic disease burden in an adult community sample: a cross-sectional study

Tabajonda JAQ, Yang SH, Shen YL, Mesina FZ, Sabit MB, Sy Ortin TT, Tan CLB, Pang CY, Li CC, Chen LY, Albano PMSP. Lab Med. 2026
Shorter donor leukocyte telomere length is associated with poor peripheral blood stem cell mobilization induced by granulocyte colony-stimulating factor

Yang SH, Liu HT, Wang TF, Liou YS, Sun DS, Wang JH, Chen LY. J Formos Med Assoc. 2025
Role of the cGAS–STING pathway in cancer development and oncotherapeutic approaches

Khoo LT and Chen LY EMBO reports 2018
Extrachromosomal telomere repeat DNA is linked to ALT development via cGAS-STING DNA sensing pathway

Chen YA, Shen YL, Hsia HY, Tiang YP, Sung TL, Chen LY Nat. Struct. Mol. Biol. 2017
Chemotherapy for extracranial germ cell tumors in paediatric, adolescent, and young adult patients

Chen RL, Lin HT, Chen LY EMJ Oncology 2017
No DDrama at chromosome ends: TRF2 takes centre stage

Feuerhahn S, Chen LY, Luke B, Porro A Trends Biochem Sci. 2015
Molecular basis of telomere syndrome caused by CTC1 mutations

Chen LY , Majerská J, Lingner J Genes Dev. 2013
CST for the grand finale of telomere replication

Chen LY and Lingner J Nucleus 2013
Phosphorylation of TPP1 regulates cell cycle-dependent telomerase recruitment

Zhang Y, Chen LY, Han X, Hie W, Kim H, Yang D, Liu D, Songyang Z Proc Natl Acad Sci U S A. 2013
Mitochondrial Localization of telomeric protein TIN2 links telomere regulation to metabolic control

Chen LY, Zhang Y, Li H, Zhang Q, Fang H, Yotnda P, Kim SH, Qin L, Xu J, Tu B, Bai Y, Sonagyang Z Mol Cell 2012
The human CST complex is a terminator of telomerase activity

Chen LY, Redon S, and Lingner J Nature 2012
AUF1/hnRNP D RNA binding protein functions in telomere maintenance

Chen LY and Lingner J Mol Cell 2012
CHMP6 and VPS4A mediate the recycling of Ras to the plasma membrane to promote growth factor signaling

Zheng ZY, Cheng CM, Fu XR, Chen LY, Xu L, Terrillon S, Wong ST, Bar-Sagi D, Songyang Z, and Chang EC Oncogene 2012
Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells

Lee OH, Kim H, He Q, Baek HJ, Yang D, Chen LY, Liang J, Chae HK, Safari A, Liu D, and Songyang Z. Mol Cell Proteomics 2011
TRF2 functions as a protein hub and regulates telomere maintenance by recognizing specific peptide motifs

Kim H, Lee OH, Xin H, Chen LY, Qin J, Chae HK, Lin SY, Safari A, Liu D, and Songyang Z Nat Struct Mol Biol 2009
Daxx contains two nuclear localization signals and interacts with importin alpha3.

Yeung PL, Chen LY, Tsai SC, Zhang A, and Chen JD J Cell Biochem 2008
Telomere maintenance through spatial control of telomeric proteins.

Chen LY, Liu D, and Songyang Z Mol Cell Biol 2007
Regulation and binding of pregnane X receptor by nuclear receptor corepressor silencing mediator of retinoid and thyroid hormone receptors (SMRT)

Johnson DR, Li CW, Chen LY, Ghosh JC, and Chen JD Mol Pharmacol 2006
Daxx silencing sensitizes cells to multiple apoptotic pathways.

Chen LY, and Chen JD Mol Cell Biol 2003

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